홈> 제품정보 > 시약 > 해외 공식 대리점 >[io1001] ioGlutamatergic Neurons
[io1001] ioGlutamatergic Neurons
제품코드 : io1001
제품정보 : ioGlutamatergic Neurons
Human iPSC-derived glutamatergic neurons
ioGlutamatergic Neurons are deterministically programmed from human induced pluripotent stem cells (iPSC) using opti-ox technology. Within days, cells convert consistently to mature, functional excitatory neurons characterised by >80% expression of glutamate transporter genes VGLUT1 and VGLUT2.
Glutamatergic neurons are highly defined and characterised, and are delivered cryopreserved and ready-to-culture, making them a high-quality, easy-to-use, human model for translational research, disease modelling and drug discovery.
In addition to the wild type, our portfolio includes glutamatergic neurons carrying disease-relevant mutations for studying ALS, FTD, Alzheimer's, Parkinson's, Gaucher and Huntington's diseases, and CRISPR-Ready glutamatergic neurons stably expressing Cas9 nuclease or dCas9 variants for rapid gene knockouts, activations or repressions.
Applications: Drug discovery, Neurotoxicology, Electrophysiology, High throughput screening, CRISPR Screening, 3D bioprinting