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홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1007] ioGlutamatergic Neurons GBA Null/R159W
[io1007] ioGlutamatergic Neurons GBA Null/R159W
제품코드 : io1007
제품정보 : ioGlutamatergic Neurons GBA Null/R159W
- Human iPSC-derived Gaucher and Parkinson’s disease model ioGlutamatergic Neurons GBA null/R159W are opti‑ox deterministically programmed excitatory neurons carrying a genetically engineered compound heterozygous mutation in the GBA gene encoding the glucocerebrosidase (GCase) enzyme. These cells offer a rapidly maturing, human cell model to investigate modulation of GCase expression. Related Parkinson's disease model cells are available with PINK1 Q456X, PRKN R275W and SNCA A53T mutations, and all can be used alongside their genetically matched control, ioGlutamatergic Neurons. Applications: Gaucher and Parkinson's disease research, Drug discovery and development, Disease modelling
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