(주) 드림셀-생명공학 실험실용 시약, 기기, 소모품

홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1020] ioGlutamatergic Neurons PRKN R275W/R275W

제품코드 : io1020

제품정보 : ioGlutamatergic Neurons PRKN R275W/R275W

Human iPSC-derived Parkinson's disease model ioGlutamatergic Neurons PRKN R275W/R275W are opti‑ox deterministically programmed excitatory neurons carrying a genetically engineered homozygous mutation in the PRKN gene encoding the Parkin protein. These cells offer a rapidly maturing, disease relevant and isogenic system for investigating the molecular and cellular significance of a homozygous R275W mutation in Parkinson’s disease. This disease model is part of a Parkinson's disease panel of physiologically relevant human iPSC-derived cells that can be incorporated into translational research and drug discovery workflows. Additional mutations in the PD panel include a heterozygous PRKN R275W mutation, homozygous and heterozygous PINK1 Q456X, SNCA A53T and GBA mutations. All can be used alongside their genetically matched control, ioGlutamatergic Neurons. Applications: Parkinson's disease research, Drug discovery and development, Disease modelling

인류의 건강과 생명공학 발전을 위해 봉사하는 기업 드림셀