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홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1024] ioSensory Neurons
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[io1024] ioSensory Neurons

제품코드 : io1024

제품정보 : ioSensory Neurons

  • Highly pure human iPSC-derived sensory neurons with a defined nociceptor identity ioSensory Neurons are a highly pure, easy to use and functional in vitro nociceptor model, enabling reliable chronic nociceptive pain research and therapeutics development for peripheral neuropathies. ioSensory Neurons are deterministically programmed using opti-ox technology meaning consistency is built-in. Within 7 days post-revival, ioSensory Neurons form a highly pure (>99%) sensory neuronal population with a defined nociceptor identity, characterised by the expression of the pan-sensory neuron markers, PRPH, BRN3A, ISL1 and TUBB3, and key markers of nociceptors, NTRK1 and TRPV1. These cells display spontaneous activity and show a functional nociceptor phenotype, as demonstrated by responsiveness to selective agonists for TRPV1, TRPM3, and TRPM8. Applications: Chronic pain research & drug development, MEA analysis, Calcium imaging, Transcriptome analysis, Neurotoxicology

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    2292-8870

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