홈> 제품정보 > 시약 > 해외 공식 대리점 >[io1024] ioSensory Neurons
[io1024] ioSensory Neurons
제품코드 : io1024
제품정보 : ioSensory Neurons
Highly pure human iPSC-derived sensory neurons with a defined nociceptor identity
ioSensory Neurons are a highly pure, easy to use and functional in vitro nociceptor model, enabling reliable chronic nociceptive pain research and therapeutics development for peripheral neuropathies.
ioSensory Neurons are deterministically programmed using opti-ox technology meaning consistency is built-in. Within 7 days post-revival, ioSensory Neurons form a highly pure (>99%) sensory neuronal population with a defined nociceptor identity, characterised by the expression of the pan-sensory neuron markers, PRPH, BRN3A, ISL1 and TUBB3, and key markers of nociceptors, NTRK1 and TRPV1.
These cells display spontaneous activity and show a functional nociceptor phenotype, as demonstrated by responsiveness to selective agonists for TRPV1, TRPM3, and TRPM8.
Applications: Chronic pain research & drug development, MEA analysis, Calcium imaging, Transcriptome analysis, Neurotoxicology