홈> 제품정보 > 시약 > 해외 공식 대리점 >[io1028] ioOligodendrocyte-like cells
[io1028] ioOligodendrocyte-like cells
제품코드 : io1028
제품정보 : ioOligodendrocyte-like cells
Human iPSC-derived oligodendrocyte-like cells
ioOligodendrocyte-like cells are highly characterised cells that resemble a pre-myelinating oligodendrocyte state. These cells enable the screening of compounds that modulate myelination, supporting drug development for neurodegenerative and demyelinating diseases, such as multiple sclerosis.
ioOligodendrocyte-like cells are deterministically programmed using opti-ox technology, meaning scalability and consistency are built-in.
Upon thawing (day 1), cells are ready for experimentation and express the oligodendroglial lineage marker O4. By simply maintaining cells in a monolayer culture, cells rapidly mature and acquire a typical oligodendrocyte-like morphology with multiple branched processes. Cells start expressing oligodendrocyte markers, including MBP, PLP1, CNP and MAG.
Applications: Screening of compounds that modulate myelination, Phenotypic assays, Target validation, Neurotoxicity assays, Neuroinflammation assays