홈> 제품정보 > 시약 > 해외 공식 대리점 >[io1041] ioMotor Neurons SOD1 G93A/G93A (CL11)
[io1041] ioMotor Neurons SOD1 G93A/G93A (CL11)
제품코드 : io1041
제품정보 : ioMotor Neurons SOD1 G93A/G93A (CL11)
Human iPSC-derived ALS disease model
ioMotor Neurons SOD1 G93A/G93A are opti‑ox deterministically programmed ioMotor Neurons carrying a genetically engineered homozygous mutation in the SOD1 gene encoding the Superoxide dismutase 1 protein.
Within days, cells convert to a defined and scalable genetically matched system for investigating the molecular and cellular significance of a homozygous G93A mutation in ALS.
Related disease model cells are available with a heterozygous SOD1 G93A/WT mutation, and both can be used alongside their genetically matched control, ioMotor Neurons.
Additional disease models are available in ioGlutamatergic Neurons with mutations in TDP‑43 and MAPT, creating a comprehensive toolkit to study the genetic and pathological overlap between ALS and FTD.
Applications: Neurodegeneration research, ALS disease modelling, Electrophysiological analysis, Drug development & discovery, Neuromuscular research, Neurotoxicology