(주) 드림셀-생명공학 실험실용 시약, 기기, 소모품

홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1052] ioMotor Neurons FUS P525L/P525L (CL4)

제품코드 : io1052

제품정보 : ioMotor Neurons FUS P525L/P525L (CL4)

Human iPSC-derived ALS disease model ioMotor Neurons FUS P525L/P525L are opti‑ox deterministically programmed ioMotor Neurons carrying a genetically engineered homozygous mutation in the FUS gene encoding the Fused in Sarcoma protein. Within days, cells convert to a defined and scalable genetically matched system for investigating the molecular and cellular significance of a homozygous P525L mutation in ALS. Related disease model cells are available with a heterozygous FUS P525L/WT mutation, and both can be used alongside their genetically matched control, ioMotor Neurons. Additional disease models are available in ioGlutamatergic Neurons with mutations in TDP‑43 and MAPT, creating a comprehensive toolkit to study the genetic and pathological overlap between ALS and FTD. Applications: Neurodegeneration research, ALS disease modelling, Electrophysiological analysis, Drug development & discovery, Neuromuscular research, Neurotoxicology

인류의 건강과 생명공학 발전을 위해 봉사하는 기업 드림셀