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홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1055] ioMotor Neurons FUS P525L/WT (CL71)
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[io1055] ioMotor Neurons FUS P525L/WT (CL71)

제품코드 : io1055

제품정보 : ioMotor Neurons FUS P525L/WT (CL71)

  • Human iPSC-derived ALS disease model ioMotor Neurons FUS P525L/WT are opti‑ox deterministically programmed ioMotor Neurons carrying a genetically engineered heterozygous mutation in the FUS gene encoding the Fused in Sarcoma protein. Within days, cells convert to a defined and scalable genetically matched system for investigating the molecular and cellular significance of a heterozygous P525L mutation in ALS. Related disease model cells are available with a homozygous FUS P525L/P525L mutation, and both can be used alongside their genetically matched control, ioMotor Neurons. Additional disease models are available in ioGlutamatergic Neurons with mutations in TDP‑43 and MAPT, creating a comprehensive toolkit to study the genetic and pathological overlap between ALS and FTD. Applications: Neurodegeneration research, ALS disease modelling, Electrophysiological analysis, Drug development & discovery, Neuromuscular research, Neurotoxicology

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