(주) 드림셀-생명공학 실험실용 시약, 기기, 소모품

홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1076] ioGlutamatergic Neurons PINK1 Q456X/Q456X (CL77)

제품코드 : io1076

제품정보 : ioGlutamatergic Neurons PINK1 Q456X/Q456X (CL77)

Human iPSC-derived Parkinson's disease model ioGlutamatergic Neurons PINK1 Q456X/Q456X are opti‑ox deterministically programmed excitatory neurons carrying a genetically engineered homozygous Q456X mutation in the PINK1 gene encoding the protein PTEN induced putative kinase 1. These cells offer a rapidly maturing, disease relevant system for investigating the role of PINK1 Q456X mutation in early-onset Parkinson's disease (PD). This disease model is part of a Parkinson's disease panel of physiologically relevant human iPSC-derived cells that can be incorporated into translational research and drug discovery workflows. An additional clone for the PINK1 Q456X hom mutation is available for scientists who wish to repeat their experiments in multiple independent clones, please enquire. Additional mutations in the PD panel include a heterozygous PINK1 Q456X mutation, PRKN R275W, SNCA A53T and GBA mutations. All can be used alongside their genetically matched control, ioGlutamatergic Neurons. Applications: Parkinson's disease research, Drug discovery and development, Disease modelling

인류의 건강과 생명공학 발전을 위해 봉사하는 기업 드림셀