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홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io1088] ioGlutamatergic Neurons SNCA A53T/A53T (clone H5)
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[io1088] ioGlutamatergic Neurons SNCA A53T/A53T (clone H5)

제품코드 : io1088

제품정보 : ioGlutamatergic Neurons SNCA A53T/A53T (clone H5)

  • Human iPSC-derived Parkinson's disease model A rapidly maturing, consistent and scalable isogenic system to study Parkinson’s disease (PD). ioGlutamatergic Neurons SNCA A53T/A53T are opti-ox deterministically programmed excitatory neurons carrying a genetically engineered homozygous A53T mutation in the SNCA gene encoding the alpha-synuclein protein. This disease model is part of a Parkinson’s disease panel of human iPSC-derived cells that can be incorporated into translational research and drug discovery workflows. Two additional clones for the SNCA A53T hom mutation are available for scientists who wish to repeat their experiments in multiple independent clones, please enquire. All disease models are genetically matched to the wild-type control, ioGlutamatergic Neurons. Additional mutations in the PD panel include heterozygous SNCA A53T, het and hom PINK1 Q456X, PRKN R275W and GBA mutations. Applications: Parkinson's disease research, Drug discovery and development, Disease modelling

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