(주) 드림셀-생명공학 실험실용 시약, 기기, 소모품

홈 > 제품정보 > 시약 > 해외 공식 대리점 > [io6005] ioGlutamatergic Neurons SNCA A53T/WT (621P2D1)

제품코드 : io6005

제품정보 : ioGlutamatergic Neurons SNCA A53T/WT (621P2D1)

Human iPSC-derived Parkinson's disease model ioGlutamatergic Neurons SNCA A53T/WT are opti‑ox deterministically programmed excitatory neurons carrying a genetically engineered heterozygous A53T mutation in the SNCA gene encoding the alpha-synuclein protein. These cells offer a rapidly maturing, consistent and scalable system to study Parkinson's disease (PD). This disease model is part of a Parkinson's disease panel of physiologically relevant human iPSC-derived cells that can be incorporated into translational research and drug discovery workflows. Additional products in the PD panel include homozygous SNCA A53T, PRKN R275W, PINK1 Q456X and GBA mutations. All disease model cells in the PD panel can be used alongside their genetically matched control, ioGlutamatergic Neurons. A second SNCA A53T/WT clone is available on enquiry. Studying multiple clones of a specific disease model can lead to a more comprehensive understanding of the impact of the disease-relevant mutation and cellular heterogeneity on associated disease phenotypes. Applications: Parkinson's disease research, Drug discovery and development, Disease modelling

인류의 건강과 생명공학 발전을 위해 봉사하는 기업 드림셀