홈> 제품정보 > 시약 > 해외 공식 대리점 >[io6021] ioSkeletal Myocytes DMD Exon 45 Deletion
[io6021] ioSkeletal Myocytes DMD Exon 45 Deletion
제품코드 : io6021
제품정보 : ioSkeletal Myocytes DMD Exon 45 Deletion
Human iPSC-derived Duchenne muscular dystrophy model
ioSkeletal Myocytes DMD Exon 45 Deletion are opti‑ox deterministically programmed skeletal myocytes carrying a genetically engineered hemizygous deletion in exon 45 of the DMD gene encoding the dystrophin protein. These cells offer a rapidly maturing, consistent, scalable system to study Duchenne muscular dystrophy in a functional human cell model.
This disease model is part of a Duchenne muscular dystrophy panel of physiologically relevant human iPSC-derived cells that can be incorporated into translational research and drug discovery workflows. The panel includes DMD exon 44, exon 51 and exon 52 deletions. All can be used alongside their genetically matched control ioSkeletal Myocytes.
Applications: Muscle and neuromuscular research, Disease modelling, Contractility assays, 3D muscle tissue engineering